Monday, October 15, 2018

What is Diabetes mellitus type 2

February 19, 2013 by  
Filed under Causes & Symptoms

Diabetes Mellitus (or simply diabetes) is derived from the Greek word ‘Diabeinein’, meaning ‘To pass through’ describing copious urination, and Mellitus from the Latin word meaning ‘Sweetened with honey’. These two words signify sweetened urine or sugar in urine.

diabetes

Type 1 or 2 Diabetes Mellitus is a disease in which the body does not produce or properly use Insulin. Insulin is a hormone that is needed, in the body, to control the rate at which sugar, starch and other food are converted into glucose required as energy for daily life. The hormone is produced and released into the blood by an organ called ‘Pancreas’. This insulin help to maintain the blood glucose level within a normal range. The American Diabetes Association puts this normal range between 4.4 to 6.1 mmol/L (82 and 110mg/dl) (Before taking any food for the day, hence this value is called Fasting Blood Glucose). In health, despite several demands for glucose in different situations, the blood glucose rarely exceeds this value.

After a meal the liver stores the glucose from the meal as glycogen and releases it into the blood in between meals. The role of insulin is the control of this storage and release of glucose. It ensures that the amount of glucose in the blood at every particular time does not go beyond or below the normal range.

TYPES OF DIABETES.

According to the World Health Organization (WHO), five classes of diabetes are recognized, these are; Insulin Dependent Diabetes Mellitus (IDDM) or Type 1 Diabetes, Non Insulin Dependent Diabetes Mellitus (NIDDM) or Type 2 Diabetes, Gestational Diabetes, Diabetes Insipidus and Bronze Diabetes.

INSULIN DEPENDENT/TYPE 1 DIABETES: This type of diabetes was initially called Juvenile onset diabetes because it affects adolescents and young adults. It is caused by a sudden failure of the pancreas to produce Insulin. It is, therefore, an acute disease, presenting with thirst, polyuria (passing large amount of urine), diuresis and weight loss. Type I diabetes is not common, it accounts for less than 10% of all diabetes cases.

NON-INSULIN DEPENDENT/ TYPE 2 DIABETES: This is the most prevalent type of diabetes, accounting for more than 80% of all diabetic cases. It is found in adults and the elderly. This type of diabetes develops gradually over a long period of time (unnoticed) and is characterized by insufficient insulin, deficient insulin in the blood or the inability of the body to utilize the insulin resent (Insulin resistance). Because of its slow and gradual occurrence, it is mostly undetected until one or more of its long-term complications appear.

Unlike in Type one Diabetes, the Insulin in the blood of a Type two diabetic may be normal or even high, but lacks the desired effect, due to insulin resistance, and this is prevalent among obese people.

GESTATIONAL DIABETES: This type of diabetes occurs during pregnancy and disappears after delivery, within 3weeks. An estimated 3% of all pregnancies are accompanied by gestational diabetes and almost half of these patients are prone to developing permanent diabetes later in life.

WHAT CAUSES DIABETES?

As with hypertension and other non communicable diseases, no clear cut cause(s) can be attributed to the most prevalent type of diabetes (Type II Diabetes, Type I diabetes being secondary to failure of the pancreas). However, some factors are known to increase one’s chances of becoming diabetic and these are called risk factors. For example, indolent and well-fed populations are 2 ? 20times more likely to develop type II diabetes than active and lean population of the same race. Some other factors known to increase one chances of getting diabetes include:

OBESITY: It is estimated that three quarters (¾) of all Type two diabetics are obese. Indolent and affluent lifestyles tend to contribute to this. It is believed that a 10kg loss of weight can reduce fasting blood sugar level by almost 2.75mmol/L or 50mg/dl. An active lifestyle with frequent exercise is also known to increase Insulin sensitivity.

The International standard for measuring overweight and obesity is based on a value called BODY MASS INDEX (BMI). This value is derived by dividing the body weight (in Kilograms) by the square of height (in metres).

i.e. BMI = Body weight (Kg) / Height2 (Metres).
Note: 1ft = 0.305metres.

For adults, a BMI less than 25kg/m2 is preferred.

25 to 29kg/m2 is considered overweight and above 30kg/m2 is Obesity.

FAMILY HISTORY: A family history of diabetes increases one’s chances of getting the disease. In such a situation, leading a healthy lifestyle and constant monitoring of one’s blood sugar level becomes very important. AGE AND RACE: Most Type II diabetes patient are over 40yrs at presentation of the disease. However, the proportion of increase in the incidence of this disease with age is higher for those with a family history of diabetes, obese and probably those leading sedentary lifestyles. Moreover, diabetes tends to be more prevalent among Africans, African Americans, Latinos, Native Americans and Asian Americans. Belonging to any of the races is a risk factor in itself.

HISTORY OF GESTATIONAL DIABETES: in a woman also increases her chances/possibility of developing permanent diabetes later in life.

YOU CAN PREVENT/DELAY DIABETES! Diabetes have no permanent cure once it develops, it is managed all through life. But you can prevent ever falling into this life long pain. Before diabetes present in people, it is almost always preceded by a situation called PRE DIABETES. A situation where the blood glucose is higher than normal, but not yet enough to be diagnosed as diabetes. Saddening, however, you cannot know when you fall into this category, if you have not being monitoring your blood glucose regularly.

Pre Diabetes is itself a serious medical situation, though can still be reversed by making changes in diet pattern and increasing physical activity. To determine one’s blood sugar a test called Fasting Blood Glucose has to be conducted. This test measures the amount of glucose (sugar) in one’s blood before taking any meal for the day. It is measured in millimoles per litre (mmol/L) or  milligrams per deciliter (mg/dl).

A value below 5.5mmol/L or 100mg/dl is generally accepted to be normal, while a value greater than 5.5mmol/L/100mg/dl but less than 6.6mmol/L/120mg/dl is not full diabetes yet, so it is regarded as Pre diabetes. An individual with a pre diabetes blood glucose level needs to take urgent steps to reduce his blood glucose or risk life long diabetes.

It should be emphasized, however, that the racial and genetic factors predisposing to diabetes are still beyond human comprehension and control. It makes common sense, therefore, to reduce all human controllable factors to the barest minimum. Most of these factors have to do with social occupational and diet habits.

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